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Sleep apnoea: a common condition that often goes undiagnosed

Plain information for patients in Singapore about obstructive sleep apnoea: what it is, the signs to look out for, how a sleep study diagnoses it, and why it is worth finding out.

A dimly lit bedroom at night, with an empty bed, two pillows and city lights behind sheer curtains
Sleep apnoea happens during sleep, so the person who has it is often the last to notice. A bed partner may hear the snoring or the pauses first.

This is general health information, not medical advice. If you think you may have sleep apnoea, or you are very sleepy during the day, please see a doctor. If you are sleepy at the wheel, do not drive until you have been assessed.

What sleep apnoea is

In obstructive sleep apnoea, the airway at the back of the throat narrows or closes again and again during sleep. Each time, breathing becomes shallow or stops for a few seconds, the oxygen level in the blood drops, and the brain briefly wakes the body up to reopen the airway. This can happen many times an hour, usually without the person remembering it.[1]

The result is sleep that is broken into pieces, even when it seems to last all night. That is why people with sleep apnoea often wake up unrefreshed however long they sleep.

Signs to look out for

Night-time signs, often noticed by someone else first:[2]

Daytime signs:

Not everyone who snores has sleep apnoea, and not everyone with sleep apnoea snores loudly. The only way to know is a sleep study.

Who is more likely to have it

Why it so often goes undiagnosed

Sleep apnoea is common, and most people who have it do not know. In a community study of adults aged 21 to 79 in Singapore who had a sleep test at home, 30.5% had moderate to severe sleep-disordered breathing, and 91% of them had never been diagnosed.[5] An older study of middle-aged adults in the United States found much the same: 82% of men and 93% of women with moderate to severe sleep apnoea had not been diagnosed.[6]

There are understandable reasons for this. It happens while you are asleep. Snoring is often treated as a joke or a nuisance rather than a symptom. And tiredness, poor concentration and low mood creep up slowly, so they get put down to work, stress or age. Many people live with it for years before anyone suggests a sleep test.

How a sleep study diagnoses it

Sleep apnoea is diagnosed with a sleep study, which records your breathing and oxygen levels while you sleep. Questionnaires about snoring and sleepiness can show who is more likely to have it, but they cannot diagnose it on their own.[7]

There are two kinds of sleep study:

The study gives a count of how many times an hour your breathing stops or becomes shallow. That number is used to say whether sleep apnoea is present, and whether it is mild, moderate or severe. A doctor goes through the result with you, together with your symptoms and your health.

A home test has limits, and it is right that you know them. It can slightly underestimate how severe sleep apnoea is. If the result is negative or unclear but the symptoms are strong, a laboratory study is the next step. A laboratory study is also advised instead of a home test for some people, such as those with significant heart or lung disease, neuromuscular conditions, a previous stroke, long-term use of opioid painkillers, or severe insomnia.[7]

What it is linked to if left untreated

Repeated drops in oxygen and broken sleep night after night put strain on the heart, blood vessels and metabolism. Large long-term studies have linked untreated sleep apnoea with:

These studies show that sleep apnoea and these conditions go together, and that the link grows stronger as sleep apnoea becomes more severe. They do not all prove that sleep apnoea causes each one. Large trials have not shown that CPAP treatment prevents heart attacks or strokes. What treatment does do reliably is improve sleepiness and quality of life, and it lowers blood pressure modestly.[19][20]

How it is treated

Treatment depends on how severe the sleep apnoea is and how much it affects you. The main options in Singapore's national consensus statements are:[21]

If this sounds like you

If you, or the person who sleeps beside you, recognise the signs above, mention them to a doctor. Bring along anyone who has noticed your snoring or pauses in breathing, as what they have seen is useful. For more reading, see HealthHub's page on obstructive sleep apnoea.

Sources

  1. Yeghiazarians Y et al. Obstructive sleep apnea and cardiovascular disease: a scientific statement from the American Heart Association. Circulation 2021;144:e56-e67. doi:10.1161/CIR.0000000000000988
  2. HealthHub. Obstructive sleep apnoea. Ng Teng Fong General Hospital, reviewed 29 July 2021.
  3. Lee RW et al. Differences in craniofacial structures and obesity in Caucasian and Chinese patients with obstructive sleep apnea. Sleep 2010;33:1075-1080. doi:10.1093/sleep/33.8.1075
  4. Young T et al. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993;328:1230-1235. doi:10.1056/NEJM199304293281704
  5. Tan A, Cheung YY, Yin J, Lim WY, Tan LW, Lee CH. Prevalence of sleep-disordered breathing in a multiethnic Asian population in Singapore: a community-based study. Respirology 2016;21:943-950. doi:10.1111/resp.12747
  6. Young T, Evans L, Finn L, Palta M. Estimation of the clinically diagnosed proportion of sleep apnea syndrome in middle-aged men and women. Sleep 1997;20:705-706. doi:10.1093/sleep/20.9.705
  7. Kapur VK et al. Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American Academy of Sleep Medicine guideline. J Clin Sleep Med 2017;13:479-504. doi:10.5664/jcsm.6506
  8. Peppard PE et al. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 2000;342:1378-1384. doi:10.1056/NEJM200005113421901
  9. Logan AG et al. High prevalence of unrecognized sleep apnoea in drug-resistant hypertension. J Hypertens 2001;19:2271-2277. doi:10.1097/00004872-200112000-00022
  10. Mehra R et al. Association of nocturnal arrhythmias with sleep-disordered breathing: the Sleep Heart Health Study. Am J Respir Crit Care Med 2006;173:910-916. doi:10.1164/rccm.200509-1442OC
  11. Gottlieb DJ et al. Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the Sleep Heart Health Study. Circulation 2010;122:352-360. doi:10.1161/CIRCULATIONAHA.109.901801
  12. Yaggi HK et al. Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med 2005;353:2034-2041. doi:10.1056/NEJMoa043104
  13. Wang X et al. Obstructive sleep apnoea and the risk of type 2 diabetes: a meta-analysis of prospective cohort studies. Respirology 2013;18:140-146. doi:10.1111/j.1440-1843.2012.02267.x
  14. Tregear S et al. Obstructive sleep apnea and risk of motor vehicle crash: systematic review and meta-analysis. J Clin Sleep Med 2009;5:573-581. PMID 20465027
  15. Peppard PE et al. Longitudinal association of sleep-related breathing disorder and depression. Arch Intern Med 2006;166:1709-1715. doi:10.1001/archinte.166.16.1709
  16. Yaffe K et al. Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women. JAMA 2011;306:613-619. doi:10.1001/jama.2011.1115
  17. Young T et al. Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin sleep cohort. Sleep 2008;31:1071-1078. PMID 18714778
  18. Punjabi NM et al. Sleep-disordered breathing and mortality: a prospective cohort study. PLoS Med 2009;6:e1000132. doi:10.1371/journal.pmed.1000132
  19. McEvoy RD et al. CPAP for prevention of cardiovascular events in obstructive sleep apnea. N Engl J Med 2016;375:919-931. doi:10.1056/NEJMoa1606599
  20. Bratton DJ et al. CPAP vs mandibular advancement devices and blood pressure in patients with obstructive sleep apnea. JAMA 2015;314:2280-2293. doi:10.1001/jama.2015.16303
  21. Leow LC et al. Singapore consensus statements on the management of obstructive sleep apnoea. Ann Acad Med Singap 2025;54:627-643. doi:10.47102/annals-acadmedsg.2025153

Written for patients in Singapore.